Article
Creutzfeldt-Jacob disease associated with the PRNP codon 200Lys mutation: an analysis of 45 families.
European journal of epidemiology - 1 Sept 1991
Goldfarb L G, Brown P, Mitrovà E, Cervenáková L, Goldin L, Korczyn A D, Chapman J, Gálvez S, Cartier L, Rubenstein R
Abstract excerpt
200Lys mutation in the human PRNP coding region has been identified in 45 of the 55 CJD-affected families thus far presented to our NIH laboratory. These codon 200Lys families have a total of 87 patients, and originate from 7 different countries: Slovakia, Poland, Germany, Tunisia, Greece, Libya,...
Topics
- Africa
- Base Sequence
- Codon
- Creutzfeldt-Jakob Syndrome
- DNA, Viral
- Europe
- Family
- Genetic Testing
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction