Article
The coalescence time of sampled genes in the structured coalescent model.
Theoretical population biology - 1 Nov 2006
Notohara Morihiro, Umeda Takayoshi
Abstract excerpt
The aim of this article is to investigate the distribution of the coalescence time (T) for sampled genes in the structured coalescent. We obtain some exact solutions for small samples and approximate distributions for n sampled genes in strong and weak migration. We also conduct computer simulation to evaluate efficiencies of these approximations and show the dependency of the distribution of the coalescence time...
Topics
- Analysis of Variance
- Biological Evolution
- Chromosome Segregation
- Computer Simulation
- Emigration and Immigration
- Founder Effect
- Gene Frequency
- Genetics, Population
- Geography
- Humans
- Markov Chains
- Models, Genetic
- Mutation
- Pedigree
- Poisson Distribution
- Polymorphism, Genetic
- Selection, Genetic
- Time Factors
