3' creatine kinase (M-type) polymorphisms linked to myotonic dystrophy in Italian and Spanish populations.

doi:10.1007/BF00201719

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Article

3' creatine kinase (M-type) polymorphisms linked to myotonic dystrophy in Italian and Spanish populations.

Human genetics - 1 Oct 1991

Gennarelli M, Novelli G, Cobo A, Baiget M, Dallapiccola B

Abstract excerpt

Linkage analysis and haplotype characterization for the allelic system detected at the 3' creatine kinase muscle type (CKMM) locus were carried out in 59 myotonic dystrophy (DM) families from Italy and Spain. A maximum lod score (zmax) of 21.26 at a recombination frequency (theta) of 0.00 was fou...

Topics

Alleles
Base Sequence
Creatine Kinase
DNA
Gene Frequency
Genetic Linkage
Haplotypes
Italy
Lod Score
Molecular Sequence Data
Myotonic Dystrophy
Polymorphism, Restriction Fragment Length
Spain

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