Article
Expression and characterization of a functional canine variant of cytochrome b5 reductase.
Archives of biochemistry and biophysics - 1 Aug 2006
Roma Glenn W, Crowley Louis J, Barber Michael J
Abstract excerpt
Cytochrome b5 reductase (cb5r), a member of the flavoprotein transhydrogenase family of oxidoreductase enzymes, catalyzes the transfer of reducing equivalents from the physiological electron donor, NADH, to two molecules of cytochrome b5. We have determined the correct nucleotide sequence for the putative full-length, membrane-associated enzyme from Canis familiaris, and have generated a heterologous expression...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Catalysis
- Cytochrome-B(5) Reductase
- Dihydrolipoamide Dehydrogenase
- Dogs
- Flavin-Adenine Dinucleotide
- Gene Expression Regulation, Enzymologic
- Genetic Variation
- Kinetics
- Molecular Sequence Data
- Molecular Structure
- NADH, NADPH Oxidoreductases
- Pyridines
- Rats
- Spectrum Analysis