Article
Premature menopause in patients with BRCA1 gene mutation.
Breast cancer research and treatment - 1 Nov 2006
Rzepka-Górska Izabella, Tarnowski Bogusław, Chudecka-Głaz Anita, Górski Bohdan, Zielińska Dorota, Tołoczko-Grabarek Aleksandra
Abstract excerpt
This study was undertaken with regard to the gonadotropin theory of ovarian cancer advocated in the literature and was designed to disclose specific features of ovarian morphology in carriers of the BRCA1 gene mutation. We enrolled 171 patients and divided them into two groups: A (n=90)--operated for breast cancer (30 patients with and 60 without the BRCA1 mutation); B (n=81)--with the BRCA1 mutation qualified...
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