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Article

Downregulation of ClpR2 leads to reduced accumulation of the ClpPRS protease complex and defects in chloroplast biogenesis in Arabidopsis.

The Plant cell - 1 Jul 2006

Rudella Andrea, Friso Giulia, Alonso Jose M, Ecker Joseph R, van Wijk Klaas J

Abstract excerpt

Plastids contain tetradecameric Clp protease core complexes, with five ClpP Ser-type proteases, four nonproteolytic ClpR, and two associated ClpS proteins. Accumulation of total ClpPRS complex decreased twofold to threefold in an Arabidopsis thaliana T-DNA insertion mutant in CLPR2 designated clpr2-1. Differential stable isotope labeling of the ClpPRS complex with iTRAQ revealed a fivefold reduction in assembled...

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Identifiers

PMID: 16766689
DOI: 10.1105/tpc.106.042861
PMCID: PMC1488914

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