The effects of low-dose Bay-m-1099 (Miglitol) on serum lipids and liver enzyme activity of obese and obese-diabetic corpulent rats.

doi:10.1016/0742-8413(91)90105-3

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Article

The effects of low-dose Bay-m-1099 (Miglitol) on serum lipids and liver enzyme activity of obese and obese-diabetic corpulent rats.

Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology - 1 Jan 1991

Tulp O L, Szepesi B, Michaelis O E, DeBouno J F

Abstract excerpt

1. Groups of lean, obese, and obese-non-insulin-dependent diabetic LA/N-cp and SHR/N-cp rats were administered the a-glucosidase inhibitor Miglitol (150 mg/kg diet, ad libitum) from 8 until 15 weeks of age. 2. Phenotype effects (obese greater than lean) were present for weight gain, adiposity, se...

Topics

1-Deoxynojirimycin
Adipose Tissue
Animals
Blood Glucose
Blood Proteins
Diabetes Mellitus
Glucokinase
Glucosamine
Glucosephosphate Dehydrogenase
Glycoside Hydrolase Inhibitors
Imino Pyranoses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin

Lipids

Liver

Obesity

Phenotype

Rats

Weight Gain

Source

Open in PubMed

Identifiers

PMID: 1675969
DOI: 10.1016/0742-8413(91)90105-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1675969-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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