Article
Crystal structure and mutational analysis of the DaaE adhesin of Escherichia coli.
The Journal of biological chemistry - 4 Aug 2006
Korotkova Natalia, Le Trong Isolde, Samudrala Ram, Korotkov Konstantin, Van Loy Cristina P, Bui Anh-Linh, Moseley Steve L, Stenkamp Ronald E
Abstract excerpt
DaaE is a member of the Dr adhesin family of Escherichia coli, members of which are associated with diarrhea and urinary tract infections. A receptor for Dr adhesins is the cell surface protein, decay-accelerating factor (DAF). We have carried out a functional analysis of Dr adhesins, as well as mutagenesis and crystallographic studies of DaaE, to obtain detailed molecular information about interactions of Dr...
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