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Article

X-linked Charcot-Marie-Tooth disease. A linkage study in a large family by using 12 probes of the pericentromeric region.

Human genetics - 1 May 1991

Mostacciuolo M L, Müller E, Fardin P, Micaglio G F, Bardoni B, Guioli S, Camerino G, Danieli G A

Abstract excerpt

Linkage analysis was performed on 41 subjects belonging to a large family with a recurrence of X-linked Charcot-Marie-Tooth disease (CMTX), by using 12 restriction fragment length polymorphism markers mapping in p11-q13. The results are in agreement with previous linkage data. Three new markers that are potentially useful for genetic analysis of CMTX families are described. A more precise estimate of the...

Topics

Blotting, Southern
Charcot-Marie-Tooth Disease
Chromosome Mapping
DNA
DNA Probes
Female
Genetic Linkage
Genotype
Heterozygote
Humans
Lod Score

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Pedigree

Polymorphism, Restriction Fragment Length

X Chromosome

Source

Identifiers

PMID: 1674715
DOI: 10.1007/BF01213086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1674715-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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