Article
Novel localization of OCTN1, an organic cation/carnitine transporter, to mammalian mitochondria.
Biochemical and biophysical research communications - 14 Jul 2006
Lamhonwah Anne-Marie, Tein Ingrid
Abstract excerpt
Carnitine is a zwitterion essential for the beta-oxidation of fatty acids. We report novel localization of the organic cation/carnitine transporter, OCTN1, to mitochondria. We made GFP- and RFP-human OCTN1 cDNA constructs and showed expression of hOCTN1 in several transfected mammalian cell lines. Immunostaining of GFP-hOCTN1 transfected cells with different intracellular markers and confocal fluorescent...
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