Article
Sexually dimorphic expression of secreted frizzled-related (SFRP) genes in the developing mouse Müllerian duct.
Molecular reproduction and development - 1 Aug 2006
Cox Sam, Smith Lee, Bogani Debora, Cheeseman Michael, Siggers Pam, Greenfield Andy
Abstract excerpt
In developing male embryos, the female reproductive tract primordia (Müllerian ducts) regress due to the production of testicular anti-Müllerian hormone (AMH). Because of the association between secreted frizzled-related proteins (SFRPs) and apoptosis, their reported developmental expression patterns and the role of WNT signaling in female reproductive tract development, we examined expression of Sfrp2 and Sfrp5...
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