An investigation of sequence deletions of amelogenin (AMELY), a Y-chromosome locus commonly used for gender determination

Abstract excerpt

BACKGROUND: Accurate gender determination is crucial in many scientific disciplines, but especially so in prenatal diagnosis of X-linked diseases and forensic investigations. Today, molecular techniques, especially typing for a length variation in the X-Y homologous amelogenin gene (AMELX and AMELY), are used for gender assignation. This amelogenin test is an integral part of most PCR multiplex kits that are used...

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