Article
Conserved genes in a path from commensalism to pathogenicity: comparative phylogenetic profiles of Staphylococcus epidermidis RP62A and ATCC12228.
BMC genomics - 10 May 2006
Wei Wu, Cao ZhiWei, Zhu Yu-Li, Wang XiaoJing, Ding GuoHui, Xu Hao, Jia PeiLin, Qu Di, Danchin Antoine, Li YiXue
Abstract excerpt
BACKGROUND: Staphylococcus epidermidis, long regarded as an innocuous commensal bacterium of the human skin, is the most frequent cause of nosocomial infections associated with implanted medical devices. This conditional pathogen provides a model of choice to study genome landmarks correlated with the transition between commensalism and pathogenicity. Traditional investigations stress differences in gene content....
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