Update in Cystic Fibrosis 2005

Abstract excerpt

Cystic fibrosis (CF) is a complex, hereditary disease involving several organ systems (1).CF is caused by mutations in the gene that codes for the CF transmembrane conductance regulator (CFTR), a membrane glycoprotein that contributes to regulation of ion flux at certain epithelial surfaces.Lung disease results in most of the morbidity and mortality in CF.Advances in CF over the past several decades have recently...

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