Characterization of a Kluyveromyces lactis mutant with altered regulation of mitochondrial alcohol dehydrogenases.

doi:10.1111/j.1567-1364.2005.00013.x

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Article

Characterization of a Kluyveromyces lactis mutant with altered regulation of mitochondrial alcohol dehydrogenases.

FEMS yeast research - 1 May 2006

Mazzoni Cristina, Iacchini Simone, Serafini Agnese, Falcone Claudio

Abstract excerpt

KlADH3 and KlADH4 are Kluyveromyces lactis genes encoding the two mitochondrial alcohol dehydrogenase activities located within mitochondria. In this yeast, ethanol induces the transcription of KlADH4 and, conversely, represses that of KlADH3. In this study, we describe the effects of the aar900 mutation on such regulation. This mutation, firstly isolated in a strain devoid of alcohol dehydrogenase genes except...

Topics

Alcohol Dehydrogenase
Antifungal Agents
Benomyl
Cations, Monovalent
Chromosome Mapping
Ethanol
Gene Expression Regulation, Fungal
Kluyveromyces
Mitochondria
Mitochondrial Proteins
Mutation
RNA, Fungal
RNA, Messenger
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 16630282
DOI: 10.1111/j.1567-1364.2005.00013.x

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