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Article

Trends in drug resistance mutations in antiretroviral-naïve intravenous drug users of Rio de Janeiro.

Journal of medical virology - 1 Jun 2006

Maia Teixeira Sylvia Lopes, Bastos Francisco Inácio, Hacker Mariana A, Guimarães Monick Lindenmeyer, Morgado Mariza Gonçalves

Abstract excerpt

DNA sequencing of a pol gene fragment from drug-naive injecting drug users samples obtained at two time points of the Brazilian AIDS epidemic (Pre-HAART era: 1994 to early 1997, n = 27; post-HAART era: 1999-2001, n = 38) was undertaken to assess HIV-1 antiretroviral drug resistance mutations and subtyping profiles. Genotypic analysis revealed the presence of PR primary L90M, D30N, M46I, and V82A mutations in 7.9%...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16628575
DOI: 10.1002/jmv.20621

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