Article
A nonparametric test reveals selection for rapid flowering in the Arabidopsis genome.
PLoS biology - 1 May 2006
Toomajian Christopher, Hu Tina T, Aranzana Maria José, Lister Clare, Tang Chunlao, Zheng Honggang, Zhao Keyan, Calabrese Peter, Dean Caroline, Nordborg Magnus
Abstract excerpt
The detection of footprints of natural selection in genetic polymorphism data is fundamental to understanding the genetic basis of adaptation, and has important implications for human health. The standard approach has been to reject neutrality in favor of selection if the pattern of variation at a candidate locus was significantly different from the predictions of the standard neutral model. The problem is that...
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