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[Novel double heterozygous mutations on Met306Val and Thr181Asn related to a hereditary coagulation factor VII deficiency].

Zhonghua yi xue za zhi - 10 Jan 2006

Tu Chuan-qing, Deng Chun-yan, Wu Jian-zeng, Pan Chun-yan, Xie Chun-ying

Abstract excerpt

OBJECTIVE: To identify the genetic defect of coagulation factor VII in a Chinese family with hereditary FVII deficiency. METHODS: Peripheral blood samples were collected from the proband of hereditary FVII deficiency, female, aged 15, 4 members of her family, and 100 healthy persons. Genomic DNA was isolated. All the exons and exon-intron boundaries of FVII gene were amplified by PCR, then the PCR products were...

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PMID: 16620721

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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