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Article

Lactate increase and oxygen desaturation in mitochondrial disorders--evaluation of two diagnostic screening protocols.

Journal of neurology - 1 Apr 2006

Hanisch Frank, Müller Tobias, Muser Anett, Deschauer Marcus, Zierz Stephan

Abstract excerpt

BACKGROUND: Mitochondrial disorders are characterized by an accumulation of lactate and an insufficient oxygen extraction from blood during exercise. Therefore, both parameters (lactate and oxygen saturation) can be used as screening tests in mitochondrial disorders. However, conflicting results regarding sensitivities and specifities of both tests have been reported. METHOD: We examined 27 patients with...

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Identifiers

PMID: 16619117
DOI: 10.1007/s00415-006-0987-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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