Article
Identification of DNA sequence variation in Campylobacter jejuni strains associated with the Guillain-Barré syndrome by high-throughput AFLP analysis.
BMC microbiology - 4 Apr 2006
Godschalk Peggy C R, Bergman Mathijs P, Gorkink Raymond F J, Simons Guus, van den Braak Nicole, Lastovica Albert J, Endtz Hubert P, Verbrugh Henri A, van Belkum Alex
Abstract excerpt
BACKGROUND: Campylobacter jejuni is the predominant cause of antecedent infection in post-infectious neuropathies such as the Guillain-Barré (GBS) and Miller Fisher syndromes (MFS). GBS and MFS are probably induced by molecular mimicry between human gangliosides and bacterial lipo-oligosaccharides (LOS). This study describes a new C. jejuni-specific high-throughput AFLP (htAFLP) approach for detection and...
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