Stress-induced effects on cell-mediated innate and adaptive memory components of the murine immune response to herpes simplex virus infection.

doi:10.1016/0889-1591(91)90023-4

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Article

Stress-induced effects on cell-mediated innate and adaptive memory components of the murine immune response to herpes simplex virus infection.

Brain, behavior, and immunity - 1 Sept 1991

Bonneau R H, Sheridan J F, Feng N G, Glaser R

Abstract excerpt

Using a murine model, we have previously shown that restraint stress is able to suppress the development of herpes simplex virus (HSV)-specific cytotoxic T lymphocytes (CTL) and natural killer (NK) cell activity in the popliteal lymph nodes following local footpad infection. These studies of the primary cell-mediated immune response to HSV infection have been extended to examine the effects of a similar stressor...

Topics

Animals
Chemotaxis, Leukocyte
Cytotoxicity, Immunologic
Herpes Simplex
Immunity, Cellular
Immunologic Memory
Killer Cells, Natural
Lymphocyte Activation
Male
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Restraint, Physical

Simplexvirus

Spleen

Stress, Physiological

T-Lymphocytes, Cytotoxic

Virus Activation

Source

Open in PubMed

Identifiers

PMID: 1659472
DOI: 10.1016/0889-1591(91)90023-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1659472-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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