Article
Error propagation across levels of organization: from chemical stability of ribosomal RNA to developmental stability.
Journal of theoretical biology - 7 Sept 2006
Seligmann Hervé
Abstract excerpt
My hypothesis integrates molecular and whole-organism levels of development. A physico-chemical property of nucleotides (their dipole moment), confers structural thermostability on double-stranded sequences, and decreases chemical stability of single-stranded sequences. According to this approach, low ribosomal RNA stability should decrease the precision of protein synthesis and whole-organism developmental...
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