Article
Alpha1-antitrypsin gene polymorphisms are not associated with renal arterial fibromuscular dysplasia.
Journal of hypertension - 1 Apr 2006
Perdu Jérôme, Gimenez-Roqueplo Anne-Paule, Boutouyrie Pierre, Beaujour Sandrine, Laloux Brigitte, Nau Valérie, Fiquet-Kempf Béatrice, Emmerich Joseph, Tichet Jean, Plouin Pierre-François, Laurent Stéphane, Jeunemaitre Xavier
Abstract excerpt
OBJECTIVE: We previously showed that fibromuscular dysplasia (FMD) of the renal artery may be familial. Case reports have associated alpha1-antitrypsin deficiency and FMD. The aim of this study was to test the implication of the alpha1-antitrypsin (AAT) gene in a large cohort of patients with renal FMD. MATERIALS AND METHODS: A case-control study comparing the genotype frequencies in 161 consecutive patients with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.