Article
Structure and age of genetic diversity of dengue virus type 2 in Thailand.
The Journal of general virology - 1 Apr 2006
Zhang Chunlin, Mammen Mammen P, Chinnawirotpisan Piyawan, Klungthong Chonticha, Rodpradit Prinyada, Nisalak Ananda, Vaughn David W, Nimmannitya Suchitra, Kalayanarooj Siripen, Holmes Edward C
Abstract excerpt
Dengue virus type 2 (DENV-2) is a common viral infection and an important health concern in South-East Asia. To determine the molecular evolution of DENV-2 in Thailand, 105 isolates of the E (envelope) gene and 10 complete genomes sampled over a 27 year period were sequenced. Phylogenetic analysis of these data revealed that three genotypes of DENV-2 have circulated in Thailand, although, since 1991, only viruses...
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