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Mutations in coagulation factor XIII A gene in eight unrelated Indians. Five novel mutations identified by a novel PCR-CSGE approach.

Thrombosis and haemostasis - 1 Mar 2006

Jayandharan Giridhara R, Viswabandya Auro, Baidya Shoma, Nair Sukesh C, George Biju, Mathews Vikram, Chandy Mammen, Srivastava Alok

Abstract excerpt

Factor XIII deficiency is a rare autosomal (1:2,000,000) recessive disorder of blood coagulation usually attributed to mutations in the coagulation factor XIII (FXIII) A gene. We have studied the molecular basis of FXIII deficiency in eight unrelated South Indian patients. Their diagnosis was based on clinical history, normal plasma clotting times and increased solubility of fibrin clot in 5 mol/l urea. Genomic...

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PMID: 16525586
DOI: 10.1160/TH05-09-0617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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