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Article

Detection of a tandem BRCT in Nbs1 and Xrs2 with functional implications in the DNA damage response.

Bioinformatics (Oxford, England) - 1 Jun 2006

Becker Emmanuelle, Meyer Vincent, Madaoui Hocine, Guerois Raphaël

Abstract excerpt

MOTIVATION: Human Nbs1 and its homolog Xrs2 in Saccharomyces cerevisiae are part of the conserved MRN complex (MRX in yeast) which plays a crucial role in maintaining genomic stability. NBS1 corresponds to the gene mutated in the Nijmegen breakage syndrome (NBS) known as a radiation hyper-sensiti...

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Identifiers

PMID: 16522671
DOI: 10.1093/bioinformatics/btl075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16522671-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Detection of a tandem BRCT in Nbs1 and Xrs2 with functional implications in the DNA damage response.PMID 16522671Read ↗

NBS1 and its functional role in the DNA damage response.Semantic proximity Read ↗

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