Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neutrophils from patients with TNFRSF1A mutations display resistance to tumor necrosis factor-induced apoptosis: pathogenetic and clinical implications.

Arthritis and rheumatism - 1 Mar 2006

D'Osualdo Andrea, Ferlito Francesca, Prigione Ignazia, Obici Laura, Meini Antonella, Zulian Francesco, Pontillo Alessandra, Corona Fabrizia, Barcellona Roberto, Di Duca Marco, Santamaria Giuseppe, Traverso Francesco, Picco Paolo, Baldi Maurizia, Plebani Alessandro, Ravazzolo Roberto, Ceccherini Isabella, Martini Alberto, Gattorno Marco

Abstract excerpt

OBJECTIVE: To explore tumor necrosis factor (TNF)-induced apoptosis in neutrophils from patients with TNF receptor-associated periodic syndrome (TRAPS) and to correlate the results with the different kinds of TNFRSF1A mutations. METHODS: Two hundred sixty-five patients with clinically suspected i...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Annexin A5
Share to Apoptosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caspase 8

Share to Caspases

Share to Neutrophils

Share to Receptors, Tumor Necrosis Factor, Type I

Share to Syndrome

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 16508982
DOI: 10.1002/art.21657

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16508982-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neutrophils from patients with TNFRSF1A mutations display resistance to tumor necrosis factor-induced apoptosis: pathogenetic and clinical implications.PMID 16508982Read ↗

Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant.Semantic proximity Read ↗

Candidate genes in patients with autoinflammatory syndrome resembling tumor necrosis factor receptor-associated periodic syndrome without mutations in the TNFRSF1A gene.Semantic proximity Read ↗

A novel TNFRSF1A splice mutation associated with increased nuclear factor kappaB (NF-kappaB) transcription factor activation in patients with tumour necrosis factor receptor associated periodic syndrome (TRAPS).Semantic proximity Read ↗

A novel mutation in the third extracellular domain of the tumor necrosis factor receptor 1 in a Finnish family with autosomal-dominant recurrent fever.Semantic proximity Read ↗

Mutant tumor necrosis factor receptor associated with tumor necrosis factor receptor-associated periodic syndrome is altered antigenically and is retained within patients' leukocytes.Semantic proximity Read ↗

Proinflammatory action of the antiinflammatory drug infliximab in tumor necrosis factor receptor-associated periodic syndrome.Semantic proximity Read ↗

TNFRSF1A mutations and autoinflammatory syndromes.Semantic proximity Read ↗

Shedding of mutant tumor necrosis factor receptor superfamily 1A associated with tumor necrosis factor receptor-associated periodic syndrome: differences between cell types.Semantic proximity Read ↗

The TNF receptor-associated periodic syndrome (TRAPS): emerging concepts of an autoinflammatory disorder.Semantic proximity Read ↗

The novel S59P mutation in the TNFRSF1A gene identified in an adult onset TNF receptor associated periodic syndrome (TRAPS) constitutively activates NF-κB pathway.Semantic proximity Read ↗

Brief Report: Association of Tumor Necrosis Factor Receptor–Associated Periodic Syndrome With Gonosomal Mosaicism of a Novel 24‐Nucleotide <i>TNFRSF1A</i> DeletionSemantic proximity Read ↗

Heterogeneity among patients with tumor necrosis factor receptor-associated periodic syndrome phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.