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Rate of Elimination of Wolbachia pipientis by Doxycycline In Vitro Increases following Drug Withdrawal

22 Feb 2006

Abstract excerpt

Wolbachia pipientis is an obligate intracellular bacterium within the family Anaplasmataceae that infects many terrestrial arthropods and arthropod-transmitted nematodes (filariae). Several filarial species are major human pathogens, and antibiotics with activity against Wolbachia offer a promising new therapeutic approach, since the adult worms are relatively refractory to conventional anthelmintics but depend...

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PMID: 16495252
DOI: 10.1128/aac.50.3.922-927.2006

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Rate of Elimination of Wolbachia pipientis by Doxycycline In Vitro Increases following Drug WithdrawalPMID 16495252Read ↗

The endosymbiont Wolbachia rebounds following antibiotic treatmentSemantic proximity Read ↗

Depletion of wolbachia endobacteria in Onchocerca volvulus by doxycycline and microfilaridermia after ivermectin treatmentSemantic proximity Read ↗

Doxycycline in the treatment of human onchocerciasis: kinetics of Wolbachia endobacteria reduction and of inhibition of embryogenesis in female Onchocerca wormsSemantic proximity Read ↗

Anti-filarial Activity of Antibiotic Therapy Is Due to Extensive Apoptosis after Wolbachia Depletion from Filarial NematodesSemantic proximity Read ↗

A Cell-Based Screen Reveals that the Albendazole Metabolite, Albendazole Sulfone, Targets WolbachiaSemantic proximity Read ↗

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Macrofilaricidal activity of tetracycline against the filarial nematode <i>Onchocerca ochengi</i> : elimination of <i>Wolbachia</i> precedes worm death and suggests a dependent relationshipSemantic proximity Read ↗

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