Article
Lipoprotein glomerulopathy: a new apolipoprotein E mutation with enhanced glomerular binding.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Mar 2006
Sam Ramin, Wu Henry, Yue Lily, Mazzone Ted, Schwartz Melvin M, Arruda Jose A L, Dunea George, Singh Ashok K
Abstract excerpt
We describe a case of lipoprotein glomerulopathy, the second ever reported from the United States, in a Mexican man with a hitherto undescribed mutation in the apolipoprotein E gene (substitution of proline for arginine at position 147 [Arg147Pro]). In this patient, glomerular basement membranes showed double contours and circumferential mesangial extensions, suggesting that deposition of lipids could be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
