Article
Focal palmoplantar keratoderma caused by an autosomal dominant inherited mutation in the desmoglein 1 gene.
Dermatology (Basel, Switzerland) - 1 Jan 2006
Milingou M, Wood P, Masouyé I, McLean W H, Borradori L
Abstract excerpt
BACKGROUND: Palmoplantar keratodermas (PPK) encompass a large genetically heterogeneous group of diseases associated with hyperkeratosis of the soles and/or palms that occur either isolated or in association with other cutaneous and extracutaneous manifestations. Pathogenic mutations in the desmoglein 1 gene (DSG1) have recently been identified in a subset of patients with the striate type of PPK. OBSERVATION: We...
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