Article
Detection of premature stop codons leading to truncated internalin A among food and clinical strains of Listeria monocytogenes.
Food microbiology - 1 May 2017
Ferreira da Silva Margarida, Ferreira Vânia, Magalhães Rui, Almeida Gonçalo, Alves Artur, Teixeira Paula
Abstract excerpt
Listeria monocytogenes is a food-borne pathogen responsible for outbreaks and sporadic cases of listeriosis, a severe invasive disease. Internalin A (InlA) a protein encoded by inlA has a key role in the mechanism of pathogenesis in L. monocytogenes infection, specifically in the invasion of human intestinal epithelial cells. Studies on inlA have shown that mutations leading to premature stop codons (PMSCs) occur...
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