Article
[Collagen type IV nephropathy: from thin basement membrane nephropathy to Alport syndrome].
Orvosi hetilap - 25 Dec 2005
Endreffy Emoke, Ondrik Zoltán, Kemény Eva, Vas Zoltán, Maróti Zoltán, Lencse Gerda, Bereczki Csaba, Haszon Ibolya, Túri Sándor, Iványi Béla
Abstract excerpt
INTRODUCTION: Collagen type IV nephropathy includes the Goodpasture syndrome, thin basement membrane nephropathy and the Alport syndrome. Mutations in the coding Col(IV)A3/A4 and Col(IV)A5 genes are probable causes of the latter two. Thin basement membrane nephropathy is mostly familial and has an autosomal dominant inheritance, at least 40% of the families have hematuria that co-segregates with the Col(IV)A3...
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