Article
The glycophorin C N-linked glycan is a critical component of the ligand for the Plasmodium falciparum erythrocyte receptor BAEBL.
Proceedings of the National Academy of Sciences of the United States of America - 14 Feb 2006
Mayer D C Ghislaine, Jiang Lubin, Achur Rajeshwara N, Kakizaki Ikuko, Gowda D Channe, Miller Louis H
Abstract excerpt
Plasmodium vivax uses a single member of the Duffy binding-like (DBL) receptor family to invade erythrocytes and is not found in West Africa where its erythrocyte ligand, the Duffy blood group antigen, is missing. In contrast, Plasmodium falciparum expresses four members of the DBL family, and remarkably, single-point mutations of two of these receptors (BAEBL and JESEBL) bind to entirely different erythrocyte...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
