Article
Whole-genome association studies on alcoholism comparing different phenotypes using single-nucleotide polymorphisms and microsatellites.
BMC genetics - 30 Dec 2005
Chen Liang, Liu Nianjun, Wang Shuang, Oh Cheongeun, Carriero Nicholas J, Zhao Hongyu
Abstract excerpt
Alcoholism is a complex disease. As with other common diseases, genetic variants underlying alcoholism have been illusive, possibly due to the small effect from each individual susceptible variant, gene x environment and gene x gene interactions and complications in phenotype definition. We conducted association tests, the family-based association tests (FBAT) and the backward haplotype transmission association...
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