Article
Islands of tractability for parsimony haplotyping.
Proceedings. IEEE Computational Systems Bioinformatics Conference - 1 Jan 2005
Sharan Roded, Halldósson Bjarni V, Istrail Sorin
Abstract excerpt
We study the parsimony approach to haplotype inference, which calls for finding a set of haplotypes of minimum cardinality that explains an input set of genotypes. We prove that the problem is APX-hard even in very restricted cases. On the positive side, we identify islands of tractability for th...
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