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Article

Factor VIII gene deletions in haemophilia A patients in Czechoslovakia.

British journal of haematology - 1 Jun 1992

Krepelová A, Vorlová Z, Zavadil J, Brdicka R

Abstract excerpt

Genomic DNA from 90 Czechoslovak haemophilia A patients from 81 pedigrees was analysed by Southern blotting and hybridization with factor VIII cDNA probes. Three partial deletions of the factor VIII gene were identified and characterized: a 4.8 kilobase (kb) deletion eliminating exon 10 in one patient with severe haemophilia A without inhibitor, a 6.1 kb deletion eliminating the 3' part of intron 13 and the 5'...

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Identifiers

PMID: 1643024
DOI: 10.1111/j.1365-2141.1992.tb08219.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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