Article
Genetic complexity and gametocyte production of Plasmodium falciparum in Fulani and Mossi communities in Burkina Faso.
Parasitology - 1 May 2006
Paganotti G M, Palladino C, Modiano D, Sirima B S, Råberg L, Diarra A, Konaté A, Coluzzi M, Walliker D, Babiker H A
Abstract excerpt
We have examined Plasmodium falciparum gametocyte prevalence, density and their genetic complexity among children of 2 sympatric ethnic groups (Mossi and Fulani) in villages in Burkina Faso. The 2 groups are known to have distinct differences in their susceptibility and immune responses to malaria. We used RT-PCR and sequence-specific probes to detect and type RNA of the gametocyte-specific protein Pfs48/45....
Topics
- Age Factors
- Animals
- Anopheles
- Burkina Faso
- Child
- Child, Preschool
- Disease Susceptibility
- Ethnicity
- Genetic Variation
- Genotype
- Humans
- Infant
- Insect Bites and Stings
- Insect Vectors