Article
Autism spectrum disorders: molecular genetic advances.
American journal of medical genetics. Part C, Seminars in medical genetics - 15 Feb 2006
Bacchelli Elena, Maestrini Elena
Abstract excerpt
Despite the strong genetic basis of autism spectrum disorders (ASD), research efforts in the last decade have not been successful in the identification of confirmed susceptibility genes. We review the present status of genetic linkage, candidate gene, and association studies, pointing out the limitations of these approaches and the challenge of dealing with the clinical and genetic complexity of autism. Finally,...
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