Article
Establishment of immortalized clonal cells derived from periodontal ligament cells by induction of the hTERT gene.
Journal of oral science - 1 Dec 2005
Fujita Tomohisa, Otsuka-Tanaka Yoko, Tahara Hidetoshi, Ide Toshinori, Abiko Yoshimitsu, Mega Jun-ichi
Abstract excerpt
Since the periodontal ligament (PDL) contains a heterogeneous cell population, it is challenging to identify all cell types within the tissue and to determine whether they function alone to produce tissue components or interact with other cell types. Further, it is difficult to isolate and expand single cell clones from PDL cells, as normal cells have a limited life span and are phenotypically unstable. In the...
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