Intrafamilial heterogeneity in hereditary motor neuron disease.

doi:10.1212/wnl.42.8.1488

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Article

Intrafamilial heterogeneity in hereditary motor neuron disease.

Neurology - 1 Aug 1992

Appelbaum J S, Roos R P, Salazar-Grueso E F, Buchman A, Iannaccone S, Glantz R, Siddique T, Maselli R

Abstract excerpt

Although there are varied inheritance patterns in motor neuron disease (MND), the phenotype of MND is reported to be constant within these families, ie, cases of amyotrophic lateral sclerosis or primary lateral sclerosis do not occur in pedigrees with cases of spinal muscular atrophy. We describe...

Topics

Aged
Amyotrophic Lateral Sclerosis
Female
Humans
Male
Middle Aged
Motor Neuron Disease
Muscular Atrophy, Spinal
Pedigree
Phenotype

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