Article
A new method to remove hybridization bias for interspecies comparison of global gene expression profiles uncovers an association between mRNA sequence divergence and differential gene expression in Xenopus.
Nucleic acids research - 1 Jan 2006
Sartor Maureen A, Zorn Aaron M, Schwanekamp Jennifer A, Halbleib Danielle, Karyala Saikumar, Howell Michael L, Dean Gary E, Medvedovic Mario, Tomlinson Craig R
Abstract excerpt
The recent sequencing of a large number of Xenopus tropicalis expressed sequences has allowed development of a high-throughput approach to study Xenopus global RNA gene expression. We examined the global gene expression similarities and differences between the historically significant Xenopus laevis model system and the increasingly used X.tropicalis model system and assessed whether an X.tropicalis microarray...
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