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Distinct Transcription Profiles of Primary and Secondary Glioblastoma Subgroups

1 Jan 2006

Abstract excerpt

Glioblastomas are invasive and aggressive tumors of the brain, generally considered to arise from glial cells. A subset of these cancers develops from lower-grade gliomas and can thus be clinically classified as "secondary," whereas some glioblastomas occur with no prior evidence of a lower-grade tumor and can be clinically classified as "primary." Substantial genetic differences between these groups of...

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PMID: 16397228
DOI: 10.1158/0008-5472.can-05-0077

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