Article
Distinct ceramide synthases regulate polarized growth in the filamentous fungus Aspergillus nidulans.
Molecular biology of the cell - 1 Mar 2006
Li Shaojie, Du Liangcheng, Yuen Gary, Harris Steven D
Abstract excerpt
In filamentous fungi, the stabilization of a polarity axis is likely to be a pivotal event underlying the emergence of a germ tube from a germinating spore. Recent results implicate the polarisome in this process and also suggest that it requires localized membrane organization. Here, we employ a chemical genetic approach to demonstrate that ceramide synthesis is necessary for the formation of a stable polarity...
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