Informativeness of genetic markers for pairwise relationship and relatedness inference.

doi:10.1016/j.tpb.2005.11.003

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Article

Informativeness of genetic markers for pairwise relationship and relatedness inference.

Theoretical population biology - 1 Nov 2006

Wang Jinliang

Abstract excerpt

Measuring the information content of markers in relationship/relatedness inferences is important in selecting highly informative markers to attain a given statistical power with the minimal genotyping effort. Using information-theoretic principles, I introduce the informativeness for relationship (I(R)) and the informativeness for relatedness (I(r)) to measure the amount of information provided by markers in...

Topics

Algorithms
Animals
Bias
DNA Fingerprinting
Diploidy
Discriminant Analysis
Gene Frequency
Genes, Dominant
Genetic Markers
Genetic Variation
Genotype
Haploidy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Information Theory

Inheritance Patterns

Likelihood Functions

Microsatellite Repeats

Models, Genetic

Source

Open in PubMed

Identifiers

PMID: 16388833
DOI: 10.1016/j.tpb.2005.11.003

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