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Article

Human cytomegalovirus immediate-early 2 protein IE86 blocks virus-induced chemokine expression.

Journal of virology - 1 Jan 2006

Taylor R Travis, Bresnahan Wade A

Abstract excerpt

The effect of human cytomegalovirus (HCMV) gene expression on cytokine (beta interferon) and chemokine (RANTES, MIG, MCP-2, MIP-1alpha, and interleukin-8) expression was examined. We demonstrate that HCMV gene expression is required to suppress the transcriptional induction of these cytokines and that the HCMV immediate-early 2 gene product IE86 can effectively block the expression of cytokines and...

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Source

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Identifiers

PMID: 16378994
DOI: 10.1128/JVI.80.2.920-928.2006
PMCID: PMC1346867

Genes

MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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