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Article

Neonatal epilepsy syndromes and GEFS+: mechanistic considerations.

Epilepsia - 1 Jan 2005

Burgess Daniel L

Abstract excerpt

Genetic analyses of familial epilepsies over the past decade have identified mutations in several different ion channel genes that result in neonatal or early-onset seizure disorders, including benign familial neonatal convulsions (BFNC), generalized epilepsy with febrile seizures plus (GEFS+), and severe myoclonic epilepsy of infancy (SMEI). These genes encode voltage-gated Na+ channel subunits (SCN1A, SCN2A,...

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Share to Epilepsy, Benign Neonatal
Share to Epilepsy, Generalized
Share to KCNQ2 Potassium Channel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NAV1.1 Voltage-Gated Sodium Channel

Share to NAV1.2 Voltage-Gated Sodium Channel

Share to Potassium Channels, Voltage-Gated

Share to Receptors, Neurotransmitter

Share to Seizures, Febrile

Source

Identifiers

PMID: 16359473
DOI: 10.1111/j.1528-1167.2005.00359.x

Genes

GABRG2
KCNQ2
KCNQ3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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