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Article

Chitin induces natural competence in Vibrio cholerae.

Science (New York, N.Y.) - 16 Dec 2005

Meibom Karin L, Blokesch Melanie, Dolganov Nadia A, Wu Cheng-Yen, Schoolnik Gary K

Abstract excerpt

The mosaic-structured Vibrio cholerae genome points to the importance of horizontal gene transfer (HGT) in the evolution of this human pathogen. We showed that V. cholerae can acquire new genetic material by natural transformation during growth on chitin, a biopolymer that is abundant in aquatic habitats (e.g., from crustacean exoskeletons), where it lives as an autochthonous microbe. Transformation competence...

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PMID: 16357262
DOI: 10.1126/science.1120096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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