Article
The New World primate, Aotus nancymae, as a model for examining the immunogenicity of a prototype enterotoxigenic Escherichia coli subunit vaccine.
Vaccine - 1 May 2006
Jones Franca R, Hall Eric R, Tribble David, Savarino Stephen J, Cassels Frederick J, Porter Chad, Meza Rina, Nunez Gladys, Espinoza Nereyda, Salazar Milagros, Luckett Rickey, Scott Daniel
Abstract excerpt
The colonization factors (CF) of enterotoxigenic Escherichia coli (ETEC) are being targeted for inclusion in a multi-subunit ETEC vaccine. This study was designed to examine the preclinical safety and immunogenicity of CF CS6, encapsulated in a biodegradable poly(DL-lactide-co-glycolide) (meCS6), and administered in the presence or absence of a mutated heat-labile enterotoxin, LT(R192G), in the non-human primate,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.