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Article

RHL1 is an essential component of the plant DNA topoisomerase VI complex and is required for ploidy-dependent cell growth.

Proceedings of the National Academy of Sciences of the United States of America - 20 Dec 2005

Sugimoto-Shirasu Keiko, Roberts Gethin R, Stacey Nicola J, McCann Maureen C, Maxwell Anthony, Roberts Keith

Abstract excerpt

How cells achieve their final sizes is a pervasive biological question. One strategy to increase cell size is for the cell to amplify its chromosomal DNA content through endoreduplication cycles. Although endoreduplication is widespread in eukaryotes, we know very little about its molecular mechanisms. Successful progression of the endoreduplication cycle in Arabidopsis requires a plant homologue of archaeal DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16339310
DOI: 10.1073/pnas.0505883102
PMCID: PMC1309048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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