Article
Associations between two single nucleotide polymorphisms in the adiponectin gene and polycystic ovary syndrome.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Sept 2005
Heinonen Seppo, Korhonen Seija, Helisalmi Seppo, Koivunen Riitta, Tapanainen Juha, Hippeläinen Maritta, Laakso Markku
Abstract excerpt
In the present study we determined whether genetic variability in the gene encoding adiponectin is associated with polycystic ovary syndrome (PCOS). Altogether 143 Caucasian women with PCOS and 245 healthy controls were genotyped for two single nucleotide polymorphisms (SNPs) in exon 2 and intron 2 in the adiponectin gene. Single-point analysis was expanded to pair-of-loci haplotype analysis to examine the...
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